CPBS 7605:
Ethics for Bioinformatics

Mondays noon-2pm, October 5 - Nov 23
RC-1 South Tower, Room P18-6106

Prof. Marilyn Coors  
Office: Fulginiti Pavillion, Rm 205  
Phone: 303-724-3993  
E-mail: marilyn.coors@ucdenver.edu
Office hours by appointment 

The course will familiarize students with the ethical underpinnings of bioinformatics research. By the end of the course, students will have a vocabulary and framework by which to recognize, discuss and responsibly address ethics in computational biology research. This course is central to the educational mission of our Computational Bioscience PhD program.

Goals for the course: The course will familiarize students with the bright lines (that ought not to be crossed in the course of research), the big picture (that conceptualizes bioinformatics research in the wider world), and the deep questions (that our research activities could address). Specific learning objectives include:

1. Become familiar with the major codes of ethics governing research in computational biology, and be cognizant of examples of major lapses in biomedical research ethics.
2. Understand the broad national, international and social values that drive computational biology research priorities and activities.
3. Explore some of the major questions in ethics and values generated by contemporary biomedical research with particular emphasis on those relevant to computational biology, such as the protection of privacy.
4. Gain experience applying ethical principles, concepts and values to the conduct of research, particularly in computational biology and biomedical informatics.
5. Create a strong foundation for one's own ethical behavior throughout a career.

This isn't a lecture course. Each of the two-hour sessions will involve the students directly in discussions, role-playing exercises and other active learning approaches. Students will also be involved in selecting the topics covered and the methods by which we investigate them.

News

• Classroom has changed. We will meet in L18-6106, the Chairman's Conference Room.

Syllabus

This tentative syllabus will evolve as the course progresses. Please watch here for readings, activities, and other materials.

1. Weaving ethics into your life as a researcher; the scientist's role.
2. Handling Authorship disputes. What are the standards? Where do problems arise, and how to deal with them. Please do the readings and preparation described in the link before class Oct 12.
3. How research priorities are set: the roles of scientific, political and industrial actors. We will do the role play about authorship.
4. Discrimination against women in science. We will do the debate about the role of patient advocacy groups in funding science.
5. Using computation to solve bioethical problems.
6. The ethics of cognitive neuroenhancement in a scientific context.
7. Risks of research using biobanked materials

Grading

You must successfully complete the Responsible Conduct of Research (RCR) tutorial and self-tests from the Collaborative Institutional Training Initiative(CITI). Register for the CITI RCR courses, and complete the "Biomedical Sciences RCR Course." Choose "New Users Register Here" then select "University of Colorado at Colorado Health Sciences Center - COMIRB" from the Participating Institutions drop down list.

Your employee ID number is located in the header after you log into my.cu.edu. The institutional address is:

University of Colorado Computational Bioscience Program

12801 E. 17th Ave., Mail Stop 8303

Aurora, CO 80045

PH: 303-724-3399

Each student is expected to create an ethics portfolio, reflecting their reading, writing and thinking on ethical topics. The goal is for these portfolios to both allow the teachers to assess the students' work and to provide a vehicle to organize the student's ongoing ethical development.

You must also participate in classroom exercises and discussions. Unexcused absence from more than one course meeting is grounds for a failing grade.

Honor Code

Education at the Health Sciences Center is conducted under the honor system. All students who have entered health professional programs should have developed the qualities of honesty and integrity, and each student should apply these principles to his or her academic and subsequent professional career. All students are also expected to have achieved a level of maturity, which is reflected by appropriate conduct at all times.

Note that our educational mission statement includes even stronger goals for your professional behavior. Please feel free to raise issues related to those goals in class.